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مقاله
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Abstract
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Title:
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Effect of grid decentration on macular thickness measurements in normal subjects and patients with diabetic macular edema
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Author(s):
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Khalil Ghasemi Falavarjani MD, Joobin Khadami MD, Hamid Safi MD, Nasser Karimi MD, Foad Amirkourjani MS
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Presentation Type:
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Oral
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Subject:
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Posterior Segment and Uveitis
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Others:
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Presenting Author:
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Name:
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Khalil Ghasemi Falavarjani
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Affiliation :(optional)
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Eye Research Center, Iran University of Medical Sciences
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E mail:
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drghasemi@yahoo.com
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Phone:
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Mobile:
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09121725850
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Purpose:
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To evaluate the effect of OCT grid decentration on macular thickness measurements in normal eyes and eyes with CSME.
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Methods:
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In this prospective study, OCT 3D images of 51 eyes with CSME and 29 normal eyes were assessed. In each eye, the macular EDTRS grid was evaluated for decentration. After grid adjustment, the changes in central subfield thickness (CST) and central subfield volume (CSV) measurements were recorded. Changes > 1 micrometer (μm) and >8.5 μm in CST were considered as grid decentration and clinically significant grid decentration.
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Results:
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Grid decentration was found in 10 normal eyes (34.6%) and 32 CSME eyes (62.7%, P=0.01). Clinically significant CST changes were found in 3 normal eyes (10.3%) and 23 CSME eyes (45%, P=0.001). The mean change in CST after grid adjustment was 6.4±5.8 µm and 24.7±27 µm in normal and CSME eyes (P=0.04). Best corrected visual acuity was significantly worse in eyes with grid decentration (0.75±0.55 versus 0.42±0.22 Log MAR, P=0.02) and clinically significant grid decentration (0.81±0.6 versus 0.45±0.27 Log MAR, P=0.01).
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Conclusion:
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Grid decentration occurs in a large number of OCT thickness maps and leads to significant error in macular thickness measurements. The effect is more prominent in patients with CSME.
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Attachment:
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