|
مقاله
|
Abstract
|
|
|
Title:
|
The comparison of effectiveness and outcomes of premedication with Chloral hydrate versus midazolam-ketamine in pediatrics who underwent eye examination under general anesthesia
|
Author(s):
|
Mehdi Sanatkar, Fariba Ghasemi, Ali Reza Khodabandeh, Reza Karkhaneh, Shahram Espahbodi, Hossein Sadrossadat, Mehrdad Shoroughi, Anahid Maleki, Leyla Boojabadi
|
Presentation Type:
|
Poster
|
Subject:
|
Posterior Segment and Uveitis
|
Others:
|
|
Presenting Author:
|
|
Name:
|
Mehdi Sanatkarfar
|
Affiliation :(optional)
|
Anesthesiology and Ophthalmology Department, Farabi Hospital, Tehran University of Medical Sciences
|
E mail:
|
mehdi.sanatkar@gmail.com
|
Phone:
|
|
Mobile:
|
09121059343
|
|
|
Purpose:
|
The aim of this study was to compare the effectiveness and outcomes of premedication with chloral hydrate and midazolam-ketamine in these patients.
|
Methods:
|
A prospective randomized clinical trial was designed and 98 children aged 3 months to 6 years with ASA class 1 and 2 were included. Cases were divided randomly into two groups. The first group (n=58) received chloral hydrate 25mg/kg and another group (n=40) received midazolam 0.25mg/kg and 2.5 mg/kg ketamine. After premedication our cases underwent eye examination under general anesthesia. All patients subsequently assessed for sedation and outcomes perioperatively.
|
Results:
|
Both groups were comparable with respect to demographic and baseline characteristics. The chloral hydrate compared to midazolam-ketamine had a higher sedation success rate and longer sedation duration. The time to achieve sedation and length of stay in recovery room were not statistically significant different between two groups. The nausea and vomiting was significantly lower in chloral hydrate group. No major side effects were encountered till 24 hours in both groups. In two study groups, patients who required a second dose tended to be older and heavier.
|
Conclusion:
|
Chloral hydrate showed a significantly higher sedative effect and lower side effects than midazolam-ketamine in this study.
|
Attachment:
|
|
|