To describe a case of bilateral multiple serous retinal detachments( SRD) following bone marrow transplantation (BMT) which responded bilaterally to one session of unilateral intravitreal bevacizumab injection significantly.

Retrospective evaluation of the patient medical records

A 37 year- old – man who was complaining of gradually decreasing vision of both eyes since 3 months ago was referred to our clinic. He had a history of BMT for acute myelogenic leukemia (AML) about 4 months ago. At funduscopy there was multiple serous retinal detachments (SRD) bilaterally. With the diagnosis of multiple central serous chorioretinopathy (CSCR) , he was advised to lower the steroid dosage which did not make significant improvement; so intravitreal bavacizumab injected in the worse eye, which resulted in significant improvement bilaterally.

Serous retinal detachment is a rare complication following BMT. Significant bilateral improvement after single session unilateral intravitreal bevacizumab injection shows not only the possible role of increased level of vascular endothelial growth factor ( VEGF ) in this case, but also the systemic diffusion of the drug and contra lateral eye effect following unilateral injection.