|
مقاله
|
Abstract
|
|
|
Title:
|
Alcohol-Assisted Debridement in PRK with Intraoperative Mitomycin C.
|
Author(s):
|
Nassiri N1, Sheibani K, Safi S, Haghnegahdar M, Nassiri S, Panahi N, Mehravaran S, Nassiri N.
|
Presentation Type:
|
Oral
|
Subject:
|
Cornea and Anterior Segment
|
Others:
|
|
Presenting Author:
|
|
Name:
|
Nader Nassiri
|
Affiliation :(optional)
|
Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
|
E mail:
|
lalehofspring@yahoo.com
|
Phone:
|
22018765
|
Mobile:
|
09121465087
|
|
|
Purpose:
|
To compare corneal stromal and endothelial cells after photorefractive keratectomy with intraoperative mitomycin C in alcohol-assisted versus mechanical epithelial debridement using confocal microscopy.
|
Methods:
|
This study was performed on 88 eyes (44 patients) with myopia up to -6.00 diopters. The right eye of each patient was randomly assigned to either mechanical or alcohol-assisted groups, and the left eye was assigned to the alternate group. Confocal microscopy was performed preoperatively and at 3 months postoperatively. The main outcome measures were epithelial thickness; number of keratocytes in the anterior, mid-, and posterior stroma; and characteristics of the central corneal endothelial cells in terms of density, mean cell area, and polymegathism and hexagonality.
|
Results:
|
Three months after surgery, no statistically significant difference was noted between the study groups in terms of epithelial thickness. We also found no statistically significant difference in central corneal endothelial cells regarding cell density, mean cell area, hexagonality, or polymegathism.
|
Conclusion:
|
We found that the adverse effects of photorefractive keratectomy with mitomycin C on central corneal endothelial cells were comparable between the mechanical and alcohol-assisted epithelial debridement groups and the significant decrease in postoperative keratocyte density in anterior stroma was comparable between the two groups.
|
Attachment:
|
|
|