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مقاله
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Abstract
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Title:
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Posttraumatic endophthalmitis: responsible microorganisms and rate of resistance.
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Author(s):
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Seyed Ali Tabatabaei, Arash Mirmohammadsadeghi, Mohsen Ghadiri, Mohammad Reza Mansouri, Mohammad Riazi, Mohammad Bagher Rajabi, Mohammad Soleimani, Najaf Parandin.
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Presentation Type:
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Oral
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Subject:
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Posterior Segment and Uveitis
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Others:
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Presenting Author:
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Name:
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Ali Tabatabaei
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Affiliation :(optional)
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Tehran university of medical sciences, Farabi Eye Research Center
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E mail:
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alitabatabaei77@yahoo.com
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Phone:
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Mobile:
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09121063062
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Purpose:
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To identify the microorganisms responsible for the posttraumatic endophthalmitis and evaluate these microorganisms resistance to seven antibiotics (vancomycin, ceftazidim, ciprofloxacin, oxacillin, azithromycin, imipenem, and rifampin).
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Methods:
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: In 49 patients that underwent viterectomy for posttraumatic endophthalmitis, aqueous and vitreous samples were obtained and inoculated into blood agar, chocolate agar, and Sabouraud’s agar media. Susceptibility testing was performed with the Kirby-Bauer disk diffusion method for seven antibiotics.
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Results:
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20 patients (40.8%) had intraocular foreign bodies. The cultures were positive in 18 patients (36.7%). In all patients (except one case), one species was isolated. The most frequent isolated microorganism was staphylococcus epidermidis in 9 patients (47.4%), followed by staphylococcus aureus, bacillus species, streptococcus viridans, streptococcus pneumonia, enterococcus, diphtheroid species, and pseudomonas aeroginosa. No case with the fungal growth was seen. Each group of the microorganisms had the highest sensitivity to different antibiotics: All gram-positive cocci were sensitive to vancomycin and 73% were sensitive to ceftazidim or rifampin. All gram-positive bacilli were sensitive to vancomycin, ciprofloxacin and azithromycin. The gram-negative bacillus (pseudomonas) was sensitive to ceftazidim, ciprofloxacin, imipenem, and rifampin.
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Conclusion:
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No single antibiotic was effective against all groups of bacteria. The conventional intravitreal regimen (vancomycin+ceftazidim) seems still valuable for the treatment of bacterial endophthalmitis.
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Attachment:
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