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مقاله
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Abstract
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Title:
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Brain-derived neurotrophic factor in patients with advanced age-related macular degeneration
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Author(s):
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Mehrdad Afarid , Mohammad Torabi-Nami ,Amir Khosravi , Alijan Nemati ,Mahyar Malekzadeh
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Presentation Type:
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Poster
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Subject:
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Posterior Segment and Uveitis
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Others:
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Presenting Author:
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Name:
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Mehrdad Afarid
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Affiliation :(optional)
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Shiraz University of Medical sciences,Department of Ophthalmology, Poostchi Eye Research Center.
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E mail:
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afaridm@sums.ac.ir
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Phone:
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09177137735
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Mobile:
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09177137735
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Purpose:
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This study investigated the serum level of BDNF in AMD and healthy control subjects.
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Methods:
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36 patients with AMD and 36 age-matched controls were enrolled in this study. The serum level of BDNF was measured using the ELISA method. Results were analyzed to compare case and control values. Comparisons were also made between the BDNF level of wet- vs. dry-AMD, and male vs. female patients and controls.
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Results:
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The mean BDNF levels in AMD group (as well as in wet and dry subgroups) were significantly higher than the control group. The BDNF level however did not vary between wet- and dry-AMD patients. While within-group comparisons in males and females of AMD and control groups did not show any difference in BDNF, between-group data showed a higher mean BDNF in both male and female AMD subjects than their peer controls.
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Conclusion:
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This study demonstrated that the serum BDNF level is different in patients with AMD as compared to subjects without AMD.
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Attachment:
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4802.pptx
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