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مقاله
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Abstract
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Title:
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Comparison of the Results of two pharmaceutical product of Riboflavin in corneal collagen Cross-Linking: 18 months follow up
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Author(s):
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Hassan Hashemi1, Mohammad Amin Seyedian1, Mohammad Miraftab1, Hooman Bahrmandy1, Araz Sabzevari2, Soheila Asgari1
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Presentation Type:
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Oral
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Subject:
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Cornea and Anterior Segment
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Others:
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Presenting Author:
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Name:
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Mohammad amin Seyedian
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Affiliation :(optional)
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Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran; Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
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E mail:
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maseyedian@noorvision.com
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Phone:
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8869 1106
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Mobile:
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09121034807
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Purpose:
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: To compare the 18-month results of two formulations of Riboflavin by Sina Darou, Iran and Uznach, Switzerland, in corneal collagen cross-linking (CXL).
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Methods:
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: Sixty eyes from 60 keratoconic patients under went CXL were enrolled this study. Riboflavin by Sina Darou, Iran and Uznach, Switzerland were used in group A and B, respectively.
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Results:
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After 18 months, the mean improvement of UCVA (0.684), BCVA (0.774), and MRSE (0.785) did not differ significantly between the two groups. In group A, the mean decrease of the max- K (0.006) and mean- K (0.044) were better than group B. Mean decrease central corneal thickness 47.00±33.10 and 22.32±20.87 micron in group A and B, respectively (P=0.004). Q-value did not show any significant differences between the two groups (0.704). The two groups had no significant difference in corneal hysteresis decrease (0.062), corneal resistance factor (0.242), and endothelial cell count (0.149).
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Conclusion:
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: The results of visual acuity, refraction, corneal viscoelasticity, and ECC using Sina Darou and the Uznach formulations of Riboflavin showed that both were effective in CXL. The better flattening in group A may be related to slight difference in pre operative values.
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Attachment:
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