|
مقاله
|
Abstract
|
|
|
|
Title:
|
Comparison of prepapillary retinal nerve fiber layer thickness in bipolar disorder with normal population
|
|
Author(s):
|
Morteza Entezari, Seyed Mehdi Samimi, Mohammad Hossein Seifi, Ali Mehraban
|
|
Presentation Type:
|
Poster
|
|
Subject:
|
Posterior Segment and Uveitis
|
|
Others:
|
|
|
Presenting Author:
|
|
|
Name:
|
Morteza Entezari
|
|
Affiliation :(optional)
|
Ophthalmic Research Center, Department of Ophthalmology, Imam Hossein Medical Center, Shahid Beheshti Medical Sciences, Tehran, Iran
|
|
E mail:
|
entmort@hotmail.com
|
|
Phone:
|
22816770
|
|
Mobile:
|
09121248273
|
|
|
|
|
Purpose:
|
To compare prepapillary retinal nerve fiber layer thickness (RNFLT) between bipolar disorder and control groups by using Optical Coherence Tomography (OCT).
|
|
Methods:
|
In a prospective comparative case series, prepapillary RNFLT of 60 eyes of thirty patients with bipolar disorder compared to 60 eyes from thirty age-matched healthy control subjects. By using OCT RNFLT of the 4 prepapillary quadrants and mean of them compared between two groups.
|
|
Results:
|
The mean RNFLT was 99 ± 8, 106 ± 8 mμ in the case and control groups respectively. This difference was statistically significant (p=0.001). In comparison of the mean RNFLTs of different quadrants in the case and control groups, inferior, superior, nasal quadrants were statistically significant (p<0.001) (0.040) (0.005), temporal quadrant was not reached to the significant level (p=0.907).
|
|
Conclusion:
|
This study showed RNFLT decreases in bipolar disorder. It may be as a possible marker of neurodegeneration, and can be used for detecting severity and duration of disorder.
|
|
Attachment:
|
6996.pptx
|
|